Let’s see how. Scientists have answered the question related to the snake’s hiss. He said the snake hisses from the glottis which is connected to its respiratory system. Humans also have a glottis, which is used for speaking. When snakes breathe, this glottis opens. The glottis is connected to the snake’s trachea which connects directly to the lungs. Snakes have two lungs like humans, but only one works. The second lung is vestigial. That is to say, it disappears over time.